Research Article

Parameter Screening in Microfluidics Based Hydrodynamic Single-Cell Trapping

Figure 4

(a) obtained from numerical simulations as a function of channel inlet and outlet status combination as a sequence of ABCD (default geometry parameters are μm, μm, μm, and μm, the first cellular trapping site). Note that “I” represents the channel inlet with a defined fluid flow rate, “O” represents the channel outlet with a zero pressure, and “ ” represents the channel outlet with a zero flow rate. (b) as a function of geometry parameters for IWOW, showing that is the key parameter and it has the most significant effect on among all the four parameters.
929163.fig.004a
(a)
929163.fig.004b
(b)