High Association between Human Circulating MicroRNA-497 and Acute Myocardial Infarction

Table 3

Areas under the ROC curve and predictive value of miR-497.

	AMI (4 h)	AMI (8 h)	AMI (12 h)	AMI (24 h)
2^−ΔΔCt	2.18±0.87	6.64±4.13	3.91±2.02	1.93±0.99
95% CI	0.781–0.967	0.773–0.978	0.775–0.994	0.667–0.939
AUC	0.87	0.88	0.88	0.81
Cut-off point	1.52	1.55	1.61	1.37
Specificity (%)	90	94	95	84
Sensitivity (%)	81	82	85	80

2^−ΔΔCt, relative expression of miR-497 (mean ± SD); 95% Cl, 95% confidence interval; AUC, area under the ROC curve.