Oversimplification and Overstandardization in Biological Methods: Sperm Bioassays in Ecotoxicology as a Case of Study and a Proposal for Their Reformulation
Figure 4
Different perspectives of the relationships among dose (), exposure time (), fertilization ratio (), and response (), this last one defined as (increasing) decrease of or , as a function of the dose with respect to the control. Simulations from model (7) with the parametric values are specified in Table 1, supposing a negligible error (). The closed symbols in subfigures (B2) and (B3) correspond to the control time course and the complete dose series at time zero, respectively. The open symbols in subfigures (B2) and (B3) correspond to the different response at different doses of toxic and the different exposure times, respectively. See text and Table 1 for details.
