Cheminformatics Models for Inhibitors of Schistosoma mansoni Thioredoxin Glutathione Reductase

Table 2

The Enriched scaffolds having and enrichment factor >10 that are corresponding to 184 actives.

Scaffolds	Matches in Actives; (10735)	Matches in Inactives; (331528)	Actives; (without motif)	Inactives; (without motif)	Chi-square	-value	Enrichment factor
	13	1	10722	331527	370.9611		401.48
	16	4	10719	331524	388.9498		123.53
	11	4	10724	331524	243.3006		84.93
	20	11	10715	331517	384.4568		56.15
	21	20	10714	331508	312.045		32.43
	28	32	10707	331496	374.2882		27.02
	21	27	10714	331501	260.64		24.02
	12	21	10723	331507	119.9333		17.65
	12	30	10723	331498	89.44623		12.35
	30	92	10705	331436	184.8912		10.0