Research Article

freeQuant: A Mass Spectrometry Label-Free Quantification Software Tool for Complex Proteome Analysis

Figure 5

The analysis of functional clustering for mitochondrial proteins. Three mitochondrial proteins were involved including mouse heart mitochondrial dataset, mouse liver mitochondrial dataset, and human heart mitochondrial dataset. -axis represents different samples, -axis represents fraction of protein abundance, and the different colours represent different functional clusters. Functional annotations were distributed to 13 clusters due to biomedical properties of mitochondria. Metabolic proteins show highest abundance in mouse liver mitochondrial dataset, while oxidative phosphorylation proteins show highest abundance in cardiac mitochondrial dataset.