Bardoxolone Methyl Prevents Mesenteric Fat Deposition and Inflammation in High-Fat Diet Mice

Figure 2

Effect of bardoxolone methyl (BARD) on expression of F4/80, CD11c, and CD206 macrophages in mesenteric adipose tissue of mice fed low-fat diet (LFD), high-fat diet (HFD), and high-fat diet supplemented with BARD (HFD/BARD). (a) F4/80, CD11c, and CD206 stained sections (×40). Bar = 50 μm. The asterisks indicate F4/80 crown-like structures (CLS); the arrow heads demonstrate single F4/80, CD11c, and CD206 positive stained cells. (b) Number of CLS per high power field (HPF). (c) Number of F4/80, CD11c, and CD206 positive cells per HPF. All data are presented as mean ± SEM. ; .

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