Bardoxolone Methyl Prevents Mesenteric Fat Deposition and Inflammation in High-Fat Diet Mice

Figure 4

Effect of bardoxolone methyl (BARD) on expression of stress activated proteins in mesenteric fat tissue of mice fed low-fat diet (LFD), high-fat diet (HFD), and high-fat diet supplemented with BARD (HFD/BARD). (a) Representative blots and protein level of pSTAT3. (b) Representative blots and protein level of pAkt. (c) Representative blots and protein level of pERK. (d) Representative blots and protein level of pJNK. All data are expressed as mean ± SEM. ; ; . pSTAT3: phosphorylated signal transducer and activator of transcription 3, pAkt: phosphorylated protein kinase B, pERK: phosphorylated extracellular signal-regulated kinase, pJNK: phosphorylated c-Jun N-terminal kinase, and AU: arbitrary unit.

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