Bardoxolone Methyl Prevents Mesenteric Fat Deposition and Inflammation in High-Fat Diet Mice

Figure 5

Effect of bardoxolone methyl (BARD) on expression of rate limiting enzyme, -AR, PGC-1α, and UCP2 in mesenteric adipose tissue of mice fed low-fat diet (LFD), high-fat diet (HFD), and high-fat diet supplemented with BARD (HFD/BARD). (a) Representative blots and protein level of TH. (b) Representative blots and protein level of pTH. (c) pTH/TH ratio. (d) Representative blots and protein level of -AR. (e) Representative blots and protein level of PGC-1α. (f) Representative blots and protein level of UCP2. All data are expressed as mean ± SEM. ; . TH: tyrosine hydroxylase, pTH: phosphorylated TH; -AR: -adrenergic receptor; PGC-1α: peroxisome proliferator-activated receptor gamma coactivator 1-alpha; UCP2: uncoupling protein 2; AU: arbitrary unit.

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