Exosomes: Novel Biomarkers for Clinical Diagnosis

Table 1

Summary of exosomal proteins for clinical diagnostic applications.

Biofluid	Disease	Associated proteins	Reference
Plasma	Chronic hepatitis C	CD81	[30]
	Melanoma	CD63, caveolin-1, TYRP2, VLA-4, HSP70, HSP90	[31, 32]
	Glioblastoma	Epidermal growth factor receptor VIII	[33]
	Prostate cancer	Survivin	[34]
	Plasma cell dyscrasias	c-src	[35]
Urine	Acute kidney injury	Fetuin-A, ATF 3	[36, 37]
	Liver injury	CD26, CD81, S1c3A1, CD10	[38]
	Bartter syndrome type 1	NKCC2	[39]
	Bladder cancer	EGF, α subunit of Gs, resisitin, retinoic acid-induced protein 3, and so forth.	[40]
	Prostate cancer	PSA, PCA3	[41]
Plasma, cell culture medium, and ascites	Human ovarian cancer	L1CAM, CD24, ADAM10, EMMPRIN, claudin	[42, 43]