Study of Natural Cytotoxicity Receptors in Patients with HIV/AIDS and Cancer: A Cross-Sectional Study
Table 3
Frequency of T and NK (CD56 and CD56) cells from subjects in different groups.
Median
Mean SD
value (Kruskal-Wallis test)
Healthy
HIV/AIDS
HIV/AIDSWC
Healthy
HIV/AIDS
HIV/AIDSWC
Percentage (%)
Total lymphocytes
35.50
35.50
30.00
33.61 9.09
35.44 10.44
32.39 11.94
0.3617
T cells
55.20
59.40
57.70
54.48 11.54
60.70 9.14
57.52 11.28
0.2204
CD4 T cells
53.00
38.20
23.60
54.44 11.12
37.91 10.74
26.28 14.99
<0.0001
CD8 T cells
36.10
53.00
62.00
35.26 9.96
53.12 10.32
60.66 15.45
<0.0001
NK cells
11.30
9.70
11.60
13.21 6.69
11.15 7.08
12.93 6.75
0.4699
CD56 NK subset
96.50
95.70
94.80
95.72 2.94
94.23 5.10
93.70 5.14
0.2499
CD56 NK subset
3.70
4.50
5.10
4.41 2.99
5.26 4.14
6.37 5.60
0.3283
Absolute numbers (cells/mm3)
WBC count
7000
5500
6800
7148.00 2233.85
5924.00 1860.17
7261.90 2789.52
0.0722
Total lymphocytes
2280
1960
2110
2256.40 566.09
2007.60 597.02
2341.42 1152.39
0.4601
T cells
1159
1198
1314
1214.16 416.83
1229.88 454.55
1329.95 640.95
0.8751
CD4 T cells
655
453
280
665.36 272.59
472.56 228.92
355.42 303.63
0.0002
CD8 T cells
369
603
753
430.08 209.90
645.84 252.61
812.38 437.61
0.0007
NK cells
274
194
248
292.20 173.04
211.76 131.60
310.28 235.15
0.1501
CD56 NK subset
257
185
239
281.60 172.52
203.32 131.54
294.76 226.17
0.1817
CD56 NK subset
9
7
10
10.92 7.29
7.72 4.92
15.23 12.39
0.1137
Percentage values represent the frequency (in percentage and absolute numbers) in median of T cells, CD4 T cells, CD8 T cells, and NK cells among all peripheral blood lymphocytes and the frequency of CD56 and CD56 NK cells among the NK cell population. Means and standard deviations (SD) are also shown. Significant values are highlighted in boldface type. a = statistical difference to the healthy group (); b = statistical difference to the HIV/AIDS group (). Statistical comparisons made by Kruskal-Wallis (with Student-Newman-Keuls posttest).