Study of Natural Cytotoxicity Receptors in Patients with HIV/AIDS and Cancer: A Cross-Sectional Study
Table 4
Frequency of T and NK (CD56 and CD56) cells expressing NCRs receptors in different groups.
Median
Mean SD
p value (Kruskal-Wallis test)
Healthy
HIV/AIDS
HIV/AIDSWC
Healthy
HIV/AIDS
HIV/AIDSWC
Percentage (%) of NKp46
NK cells
72.00
50.40
69.50
70.68 22.38
48.03 19.10
61.78 21.24
0.0012
CD56 NK subset
72.50
43.00
59.60
70.13 22.80
45.38 19.75
59.69 22.13
0.0008
CD56 NK subset
93.90
92.50
95.10
93.28 5.19
92.54 6.27
93.26 6.51
0.7706
Percentage (%) of NKp30
NK cells
38.00
20.50
33.10
38.79 17.33
24.90 13.99
31.66 16.25
0.0144
CD56 NK subset
41.00
21.30
32.20
39.27 15.96
26.64 14.81
32.21 17.22
0.0286
CD56 NK subset
11.80
10.30
14.40
11.44 6.63
16.06 14.49
15.60 7.82
0.2068
Absolute numbers of NKp46 (cells/mm3)
NK cells
158
90
136
199.04 132.32
99.68 74.37
167.23 109.45
0.0018
CD56 NK subset
145
79
127
190.16 131.71
91.04 71.58
154.14 106.78
0.0019
CD56 NK subset
8
7
10
10.24 6.78
7.08 4.34
14.09 11.07
0.0754
Absolute numbers of NKp30 (cells/mm3)
NK cells
86
38
72
111.68 87.80
49.32 41.16
80.09 50.97
0.0011
CD56 NK subset
83
42
69
108.44 83.95
49.52 39.82
75.76 48.23
0.0022
CD56 NK subset
1
1
2
1.32 1.31
1.04 1.30
2.42 2.20
0.0275
The values shown represent the percentage and absolute number in median within each cell population expressing a given receptor NCR. Means and standard deviations (SD) are also shown. Significant values are highlighted in bold. a = statistical difference to the healthy group (); b = statistical difference to the HIV/AIDS group (). Statistical comparisons were made by Kruskal-Wallis (with Student-Newman-Keuls posttest).
