Recently, great achievements have been made in the mechanisms underlying heart failure development, including Ca²⁺ regulatory pathways, cardiac inflammation, and changes in cardiac immunization and metabolism. The Scientific World Journal will be publishing a special issue devoted to heart failure prevention and treatment.

Authors are invited to submit original research articles and review articles that reflect all aspects of recent advances in heart failure development and therapy, including basic and clinical studies. Potential topics include, but not limited to:

• Signaling pathways that involve heart failure development
• Regulation of myocardium contraction and relaxation
• Advances in heart failure treatment, including pharmacological and device therapy
• Recent advances in stem cells and gene therapy

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/tswj/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/tswj/cardiology/hfail/ according to the following timetable: