Research Article
Disposition Kinetics of Levofloxacin in Sheep after Intravenous and Intramuscular Administration
Table 1
Mean plasma pharmacokinetic parameters of levofloxacin (g/mL) in sheep () following IV and IM administration at a dose rate of 4 mg/kg b.w.
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: elimination rate constant; : distribution (absorption) rate constant; : distribution half-life; : absorption half-life; : elimination half-life; : volume of distribution; : total body clearance; AUC: area under the curve from zero to infinity by the trapezoidal integral; MRT: mean residence time; : maximum plasma concentration; : time to peak concentration; F(%): bioavailability; for IM, () and |