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Authors | Objective | Antioxidants | Conclusion |
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Berendschot et al. (2002) [62] | 376 subjects of 18 to 75 years. To investigate whether serum levels of antioxidants influence the lens optical density. | Lutein, zeaxanthin, Vit. C, and α-tocopherol. | High serum levels of lutein and zeaxanthin may retard aging of the lens. |
Delcourt et al. (1999) [63] | 2584 subjects, >60 years. To determine plasma levels of antioxidant enzymes related with cataract and age-related macular degeneration. | Enzymes: GPx and SOD. | High levels of plasma GPx were associated with age-related macular degeneration and cataract prevalence. High levels of plasma SOD were associated with high cataract prevalence. |
Delcourt et al. (2003) [64] | 1947 subjects, >60 years. To determine the association between antioxidant enzymes activity and incidence of cataract. | Enzymes: SOD and GPx. | High levels of plasma GPx and SOD were associated with high cataract incidence. |
Gale et al. (2001) [65] | 372 subjects of 66 to 75 years. To determine plasma levels of some vitamins and carotenoids related with cataract risk incidence. | Vit. C, Vit. E, α and β-carotene, lycopene, lutein, zeaxanthin, and β-cryptoxanthin. | High levels of α-carotene, β-carotene, lycopene and lutein were associated with low risk of cataract. |
Jacques et al. (2001) [66] | 478 women of 53 to 73 years. To assess the relation between usual nutrient intake, plasma vitamins concentration and subsequently diagnosed age-related nuclear lens opacities. | Vit. C, Vit. E, riboflavin, β-carotene, lutein, and zeaxanthin. | High Vit. C intake is associated with low risk of cataract incidence. High Vit. C and Vit. E plasma concentrations are associated with low lenticular opacity. |
Lyle et al. (1999) [67] | 400 subjects of 50 to 86 years, 7 years followup. To assess the relation of serum carotenoids and tocopherols levels to the incidence of cataract. | Carotenoids, α-tocopherol, and γ-tocopherol. | High serum levels of tocopherols are associated with low risk of cataract. |
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