The Relationship between Reactive Oxygen Species and Cardiac Fibrosis in the Dahl Salt-Sensitive Rat under ACEI Administration

Table 2

Urine 8-OHdG, plasma, tissue TBARS, and fibrosis. The detailed data relating to urine 8-OHdG, plasma, and tissue TBARS and fibrosis. Cardiac fibrosis was lowest in Group H, and there were significant differences between Group E (𝑃=0.014).

	Plasma TBARS (nmol/mL)	Urine 8-OhdG (ng/mL)	Tissue TBARS (value per protein, nmol/mg protein)	Tissue TBARS (value per weight of tissue, nmol/g)	Cardiac fibrosis (%)
Group P	5.6±2.5	5.3±0.9	1.0±0.6	61.5±35.3	2.971±0.7517
Group L	6.5±4.0	5.6±1.1	1.4±0.5	82.1±30.5	3.065±0.5602
Group H	7.2±3.5	5.8±1.2	0.8±0.5	46.4±30.2	2.744±0.6649 *
Group E	6.6±3.0	6.2±2.2	1.3±0.8	80.9±48.1	3.390±0.5650

Mean ± SD, *means significant decrease compared with Group E.