An Evaluation of MAPIA in Michigan as an Ante-Mortem Supplemental Test for Use in Suspect Tuberculosis Cattle

Table 1

Sensitivity, specificity, positive predictive value, and negative predictive value of the MAPIA test, using four different interpretation criteria.

MAPIA test criteria*	Results	True status		Test performance		Predictive value
		Positive (𝑛=49)	Negative (𝑛=185)	Sensitivity	Specificity	Positive	Negative
(1) Any positives	Positive	48	120	97.96	35.14	28.57	98.48
	Negative	1	65
(2) Two positives	Positive	46	52	93.88	71.89	46.94	97.79
	Negative	3	133
(3) Three positives	Positive	34	18	69.39	90.27	65.38	91.76
	Negative	15	167
(4) Any strong positive	Positive	29	22	59.18	88.11	56.86	89.07
	Negative	20	163

*Test criteria.
(1) Any positives: weak or strong positive reaction to at least one antigen
(2) Two positives: weak or strong positive reaction to at least two antigens
(3) Three or more positives: weak or strong positive reaction to at least three antigens
(4) Any strong positive: strong positive reaction to at least one antigen.