An Evaluation of MAPIA in Michigan as an Ante-Mortem Supplemental Test for Use in Suspect Tuberculosis Cattle

Table 3

Sensitivity, specificity, positive predictive value, and negative predictive value of weak or strong positive reactions to individual antigens used in MAPIA.

Antigen	Results	True status		Test performance		Predictive value
		Positive (𝑛=49)	Negative (𝑛=185)	Sensitivity	Specificity	Positive	Negative
ESAT-6	Positive	41	97	83.67	47.57	29.71	91.67
	Negative	8	88
ESAT-6/CFP10	Positive	43	55	87.76	70.27	43.88	95.59
	Negative	6	130
Acr1	Positive	13	9	26.53	95.14	59.09	83.02
	Negative	36	176
38 kDa	Positive	2	1	4.08	99.46	66.67	79.65
	Negative	47	184
45 kDa	Positive	24	21	48.98	88.65	53.33	86.77
	Negative	25	164
Ag85B	Positive	5	3	10.20	98.38	62.50	80.53
	Negative	44	182
GroES	Positive	14	8	28.57	95.68	63.64	83.49
	Negative	35	177
MPB83	Positive	3	0	6.12	100.0	100.0	80.09
	Negative	46	185
MPB59	Positive	1	0	2.04	100.0	100.0	79.40
	Negative	48	185
MPB64	Positive	2	0	4.08	100.0	100.0	79.74
	Negative	47	185
MPB70	Positive	24	3	48.98	98.38	88.89	87.92
	Negative	25	182