Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma

Table 2

Immunohistochemical expression of VDR, RXR, Ki-67, surviving, and ezrin in canine osteosarcoma specimens.

Marker	Cutpoint value used for expression	Proportion of cells expressing marker (percentage)*	Mean intensity of staining^# or percent positivity (range)
VDR	>0	25/33 (76%)	0.88 (0–2+)
RXR	≥5%	31/32 (97%)	76.5% (0–99%)
Ki-67	≥10%	15/26 (58%)	13.8% (1–75%)
Survivin	≥5%	25/31 (81%)	52.5% (0–98%)
Ezrin	>0	33/33 (100%)	2.7 (2-3+)

*Percentage of tumors expressing the marker within each group and number of positive samples compared to the total number of samples studied.
^#Mean staining intensity of VDR in each group.