Assessment of the Variation Associated with Repeated Measurement of Gastrointestinal Transit Times and Assessment of the Effect of Oral Ranitidine on Gastrointestinal Transit Times Using a Wireless Motility Capsule System in Dogs

Figure 2

A representative WMC system recording from a healthy dog prior to treatment with ranitidine. The pH trace is shown in green, the pressure trace in red, and the temperature trace in blue. Gastric emptying is indicated by a rapid and sustained increase in pH (a) at 12 hours and 21 minutes, assumed passage of the WMC from the small intestine to the large intestine is represented by the onset of a gradual pH decrease and a change in the character of the pressure trace (b) at 15 hours and 14 minutes, and body exit of the WMC is marked by a sharp decrease in temperature (c) at 46 hours and 6 minutes.