Pilot Study to Evaluate the Effect of Topical Dimethicone on Clinical Signs and Skin Barrier Function in Dogs with Naturally Occurring Atopic Dermatitis

<table>Mean total canine atopic dermatitis extent and severity Index (CADESI) scores as determined by the investigator. Error bars indicate <svg height="9.5625" id="M29" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 10.1 9.5625" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> standard deviation. ANOVA showed a significant effect of time with day 0 <svg height="8.9125004" id="M30" style="vertical-align:-0.04095pt" version="1.1" viewbox="0 0 10.1 8.9125004" width="10.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> day 28. The total CADESI was decreased for both the vehicle group and the dimethicone group, over time.</table>

Veterinary Medicine International

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Figure 2

Figure 2: Pilot Study to Evaluate the Effect of Topical Dimethicone on Clinical Signs and Skin Barrier Function in Dogs with Naturally Occurring Atopic Dermatitis 

Figure 2 | Pilot Study to Evaluate the Effect of Topical Dimethicone on Clinical Signs and Skin Barrier Function in Dogs with Naturally Occurring Atopic Dermatitis 