Table 2: Pharmacokinetic parameters of levofloxacin in healthy and renal damaged ducks after a single PO administration of 10 mg kg−1 bwt ( ).

ParameterUnitHealthyRenal damaged

h−1
h−1
h
h
g mL−1
h
AUC g mL−1h−1
AUMC g mL−1h−2
MRTh
MATh
F %
/MICRatio
AUC/MICRatio

, refers to degree of significance.
: first-order absorption rate constant; : elimination rate constant; : absorption half-life; : elimination half-life; : maximum plasma concentration; : time to peak plasma concentration; MAT: mean absorption time; F: fraction of drug absorbed systemically after PO administration; /MIC: maximum serum concentration/minimum inhibitory concentration ratio; AUC/MIC: area under concentration-time curve/MIC ratio.