The Relevance of CD117-Immunocytochemistry Staining Patterns to Mutational Exon-11 in c-kit Detected by PCR from Fine-Needle Aspirated Canine Mast Cell Tumor Cells
Figure 2
Two MCT histopathologic grades were classified according to the criteria of novel 2-tier histopathologic grading system [5]. (a) The low-grade MCT showed the uniformity of MCT cells in the section. The mitotic index was very low (<7 MI per 10 HPF). The multinucleated cells were rarely observed. (b) In high-grade MCT, the mitotic index was higher than 7 MI per HPF. Multinucleated cells with peculiar nuclei were commonly seen. Notably, necrotic tissues were obviously found in high-grade MCT (bar = 25 μm).
