Isolation of Oral Bacteria, Measurement of the C-Reactive Protein, and Blood Clinical Parameters in Dogs with Oral Tumor
Table 5
Comparison of the hematology and the blood chemistry profile of dogs in the no oral mass group, the oral mass group, and the metastasis group.
Parameters
Reference range
No oral mass (n = 21)
Oral mass (n = 8)
Metastasis (n = 6)
value
Blood hematology
RBC (×106cells/μL), median (IQR)
5.65–8.87
7.85 (7.57–8.12)
6.17 (4.07–6.86)
5.68 (4.44–7.1)
0.0004
WBC (×103cells/μL), median (IQR)
5.05–16.76
9.14 (8.09–10.67)
9.64 (6.69–17.46)
13.00 (10.60–16.20)
0.0886
PLT (×103cells/μL), median (IQR)
148–484
181.00 (140.00–213.00)
273.50 (142.50–375.00)
482.00 (226.00–746.00)
0.0335
NLR, median (IQR)
3.03 (2.32–3.61)
3.74 (3.08–6.50)
5.69 (4.53–6.20)
0.0032
Blood chemistry profile
TP (g/dL), median (IQR)
5.2–8.2
6.80 (6.50–7.10)
6.90 (6.65–7.20)
7.35 (6.40–7.90)
0.4680
ALB (g/dL), mean ± SD
2.2–3.9
3.10 ± 0.19
2.81 ± 0.23
2.34 ± 0.25
<0.0001
GLOB (g/dL), median (IQR)
2.5–4.5
3.60 (3.40–3.80)
4.00 (3.80–4.35)
4.40 (4.10–5.60)
0.0020
AGR, mean ± SD
0.85 ± 0.07
0.67 ± 0.11
0.50 ± 0.13
<0.0001
GAR, median (IQR)
1.15 (1.12–1.26)
1.48 (1.37–1.54)
1.78 (1.60–2.43)
0.0001
CRP (mg/L), median (IQR)
<20
<10
12.45 (10.00–23.40)
112 (105.3–116.4)
0.0001
CAR, median (IQR)
0.30 (0.29–0.33)
4.51 (3.45–9.03)
50.50 (47.00–51.00)
0.0001
BUN (mg/dL), median (IQR)
7–27
17.00 (16.00–20.00)
18.00 (13.00–22.50)
14.00 (6.00–22.00)
0.6848
CRE (mg/dL), mean ± SD
0.5–1.8
0.97 ± 0.20
0.74 ± 0.28
0.91 ± 0.41
0.1267
ALT (U/L), median (IQR)
10–125
48.00 (16.00–74.00)
43.00 (24.50–53.00)
30.00 (25.00–44.00)
0.8017
ALKP (U/L), median (IQR)
23–212
36.50 (22.00–55.50)
48.50 (28.00–93.50)
131 (83.00–311.00)
0.0017
There is the difference between the no oral mass group and the oral mass group. There is the difference between the no oral mass group and the metastasis group.There is the difference between the oral mass group and the metastasis group. RBC = red blood cell count; WBC = white blood cell count; PLT = platelet count; NLR = neutrophil to lymphocyte ratio; TP = total protein; ALB = albumin; GLOB = globulin; AGR = albumin to globulin ratio; GAR = globulin to albumin ratio; CRP = C-reactive protein; CAR = C-reactive protein to albumin ratio; BUN = blood urea nitrogen; ALT = alanine transferase; ALKP = alkaline phosphatase.
