Audrey Lau

Washington State University, USA


Education/Training: University of Hawai’i, Manoa (1987-'91) B.A. Biology University of California, Berkeley (1992-'94) M.P.H. Infectious Diseases & Immunology University of Maryland, Baltimore (1995-'00) Ph.D. Microbiology & Immunology University of California, Los Angeles (2000-'03) Postdoctoral Fellow Molecular Parasitology Washington State University (2004-'08) Postdoctoral Fellow Veterinary Microbiology & Pathology Washington State University (2004-current) Assist. Prof. Veterinary Microbiology & Pathology My research focus is on host-pathogen interactions and can be divided into two aspects: (i) the genomic basis of virulence and (ii) chemotherapeutics. My goal is to create a knowledge database that will help the field to better understand disease pathogenesis among apicomplexan parasites and, eventually, to develop novel treatments for combating diseases such as malaria and babesiosis. In fact, I have a long history of studying apicomplexan parasites and now study Babesia bovis. This model parasite offers several advantages over other apicomplexans as all experiments can be performed in the natural bovine and tick (Rhipicephalus microplus) hosts. In addition, the asexual blood stages can be routinely propagated in vitro and the parasites themselves can be genetically manipulated by transient and stable transfection. My laboratory has also sequenced several genomes of virulent and attenuated strain pairs and has even validated novel microarrays. This system and these tools are highly unique and help me to not only better understand B. bovis, but other apicomplexans as well.

Biography Updated on 24 June 2013

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