Paul Adlard

Mental Health Research Institute, Australia

My research program is centred around the basic tenant that the maintenance of normal metal ion homeostasis is crucial to the normal functioning of the brain, and furthermore, that metal ion dyshomeostasis can precipitate age-related disorders such as Alzheimer’s disease (AD), as well as more common neurological phenomena such as age-related cognitive impairment. My work has a particular focus on synaptic plasticity and learning/memory, and how the pharmacological modulation of metals in both the "normal" and "diseased" brain can impact the anatomical, biochemical and subsequent behavioural phenotypes that are associated with ageing. This is ground breaking research that will have a tangible impact on the life of older individuals suffering from a variety of age-related neurological conditions.

Biography Updated on 21 May 2012

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