Elena Jones

University of Leeds, United Kingdom


Doctor Elena Jones is an Associate Professor in Stem cell Biology in the Leeds Institute for Rheumatic and Musculoskeletal Medicine, the School of Medicine. Her post-doctoral studies were performed in Leeds Molecular Medicine Unit and were dedicated to gene therapy with stem cells. Since joining the Academic Unit of Musculoskeletal Disease, her research interests are focused on the study of human mesenchymal stem cells (MSCs) in health and disease and their use in Regenerative Medicine. In 2002 she described the phenotype of native/uncultured MSCs in human bone marrow and in 2004 she discovered MSCs in synovial fluid. Her MSC isolation methodology based on the CD271 marker has been adopted by the Industry, initially as research methodology and subsequently as a clinical-grade process. She has subsequently developed novel ideas on large-scale extraction of MSCs from surgical by-products (reaming waste bags and fatty marrow). She is currently working towards the therapeutic use of minimally-manipulated uncultured MSCs in bone repair in combination with novel scaffolds, growth factors and guided bone regeneration devices. In relation to cartilage tissue regeneration her major interest lies in the use of endogenous l MSCs in combination with biomimetic scaffolds in patients with osteoarthritis. She continues to explore the biology of synovial fluid MSCs including their homeostatic trafficking and therapeutic targeting to injured areas. Elena is a member of International Society for Cell Therapy and has been involved in organizing annual UK MSC meetings for a number of years. She has extensive experience in managing research projects, funded by the EU, Wellcome Trust, NIHR, EPSRC, ARUK and the Industry.

Biography Updated on 6 March 2018

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