Rajnish Chaturvedi is currently serving as Scientist and Assistant Professor at the Council of Scientific and Industrial Research (CSIR)-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow, India. His research interests include biochemical and molecular neurotoxicology, stem cell neurobiology, regenerative medicine, and neurodegenerative disorders. He received M.Sc. degree from Jiwaji University, India, and Ph.D. in microbiology from Jiwaji University and CSIR-IITR, Lucknow, India. He worked with the renowned neurologist Professor MF Beal at the Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, USA. He worked in the fields of cellular and molecular neurobiology and regenerative medicine. He has made efforts to increase the posttransplantation cell survival of transplanted dopaminergic neurons in the rat model of Parkinson’s disease (PD). He has identified several neurotrophic factors and neuroprotective molecules to increase the cell survival and neuroregeneration. He explored the possible cues that guide neural stem cells (NSCs) to differentiate into dopaminergic neurons and studied cellular and molecular mechanism(s) of neuroregeneration. He also studied impairment of PGC-1a and TORC1, transgenic mouse models of Huntington’s disease (HD) and HD patients. Recently, he has been involved in assessing the cellular and molecular mechanisms of neurodegenerative disorders and how environmental toxicants modulate the disease pathogenesis. He is also trying to identify the molecules which can induce “brain self-repair” by activating resident NSC population. His research group is also trying to understand how environmental toxicants affect key events of neurogenesis including regulatory cell signaling pathways and molecular and/or cellular events that are target(s) for inhibition of neurogenesis. He is recipient of several prestigious awards and fellowships and member of several international scientific societies and editorial boards of several Journals.
Biography Updated on 1 September 2013