Yan Q. Xiong

University of California, Los Angeles, USA


Yan Q. Xiong, after obtaining an M.D. degree from the Tongji Medical University, China, in 1985 and a Ph.D. degree in medical microbiology from the School of Medicine, University of Nantes, France, in 1996, she was recruited into the Laboratory of Dr. Arnold S. Bayer, a Senior Member of the Department of Medicine and Associate Chief of Adult Infectious Diseases at Geffen, School of Medicine at Harbor-UCLA Medical Center, Torrance, USA, as a Postdoctoral Research Fellow in 1997. She was appointed to the School of Medicine, UCLA as Assistant Research Professor in 2002 and promoted to Associate Research Professor in 2008. From 2008 to present, she received research Awards from NIH/NIAID and AHA (Grant-in-Aid) and severed as Co-I of four NIH/NIAID Grants and several pharmaceutical contracts. Her research efforts have focused on several main areas: 1) molecular mechanisms of Staphylococcus aureus pathogenesis in cardiovascular system; 2) pathogenic signatures of persistent methicillin-resistant S. aureus (MRSA) bacteremia and endocarditis; 3) mechanism(s) of antimicrobial agents resistance in S. aureus; and 4) interaction between endothelial cells and S. aureus in endovascular infections. Specific areas of her intensive study include the role of S. aureus virulence factors (e.g., global regulatory loci and structural genes) that contribute to the pathogenesis and responses of antibiotics and the specific role of endothelial cells in MRSA in cardiovascular infections. Her long-term goal is to discover novel antimicrobial strategies for the prevention and therapy of serious infections caused by virulent microbes, including MRSA.

Biography Updated on 3 March 2013

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