Gareth Sullivan

University of Oslo, Norway

Gareth Sullivan is a Group Leader in the Norwegian Center for Stem Cell Research and Vice Director of the Hybrid Technology Hub-Centre of Excellence in Oslo, Norway He holds a Ph.D. degree in molecular cell biology from the University of Dundee, Dundee, Scotland, and performed his Postdoctoral Research at the Centre of Regenerative Medicine, University of Edinburgh, Edinburgh, UK, with Sir Professor Ian Wilmut. In addition, he has over 8 years’ industrial experience as a CSO, working in both the toxicology and next generation sequencing fields. At the end of 2011 he established his own research group at the University of Oslo and Oslo University Hospital, where his research focus turned to what dictates cellular fate decision, along with the utilization of induced pluripotent stem cells to study disease in the dish. The overall focus of the lab now is the development of faithful liver models using human pluripotent stem cells to allow the dissection of both debilitating metabolic pediatric diseases and infectious diseases, in addition to providing tools to investigate toxicology, reducing drug failure rates, and enabling regenerative medicine. The Sullivan group was the first to demonstrate the generation of functional hepatocyte like cells from human iPSCs derived from different ethnic backgrounds (Hepatology 2010). This has led to the establishment of the first small molecule driven hepatocyte differentiation procedure (Stem Cell Reports, 2015) and is presently being translated to large-scale 3D liver organoid production, ultimately to provide a more physiological model.

Biography Updated on 18 August 2018

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