Ayman I. Sayegh

Tuskegee University, USA


Ayman I. Sayegh's laboratory is devoted to investigate the actions of certain gastrointestinal peptides or hormones (which are released as food is ingested at a meal) to determine their roles in limiting meal size and in regulating the length of the intermeal interval. At present, we are focusing on three gut peptides: cholecystokinin (from the upper intestine), PYY (from the lower intestine), and gastrin-releasing peptide (from the stomach). Our major methods include recording and analyzing moment-to-moment behavioral changes in the rat, both at the macrostructural (whole animal) and microstructural (individual lick patterns for liquid food) levels; these two perspectives reveal a comprehensive picture of changes in meal size and intermeal interval in response to the administration of the gut peptides. In addition, Sayegh's laboratory is employing immunochemical methods to identify and analyze the peripheral and central (brain) nerve sites and pathways mediating the satiating and satiety actions of these agents. His education includes a Ph.D. degree in neuroscience from Washington State University, Pullman, WA, USA, internship in equine medicine and surgery from the University of Illinois at Urbana-Champaign, IL, USA, clinical rotations and classes in equine medicine and surgery from Purdue University, West Lafayette, IN, USA, an M.S. degree from Kansas State University, Manhattan, KS, USA, and a D.V.M. degree from Baghdad University, Baghdad, Iraq. Currently, Sayegh works as a Professor of biomedical sciences at College of Veterinary Medicine, Tuskegee University, Tuskegee, AL, USA.

Biography Updated on 6 November 2012

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