Jean-Baptiste O. Roullet

Oregon Health & Science University, USA

Jean-Baptiste O. Roullet works as a Research Associate Professor in the Department of Pediatrics at the Oregon Health & Science University in Portland, Ore, USA. Dr. Roullet earned degrees in pharmacy and laboratory medicine in Paris, France, and practiced clinical chemistry for several years before joining the OHSU faculty in 1989. He also earned two Doctorate degrees from universities in Paris, in 1982 and 1998. Dr. Roullet has published several high-impact publications in the field of lipid metabolism and function, vascular physiology, and pharmacology. He is the lead author in the report that first characterized the regulatory role of endogenous alcohols in mammalian neuronal signaling and has discovered a highly promising link between these alcohols and the Sjögren-Larsson Syndrome, a rare inherited metabolic disease affecting children. He worked as principal investigator or coinvestigator on studies on the mechanisms underlying alcohol toxicity, novel treatments of alcohol withdrawal and stroke, diabetes prevention in children, and diet and learning in children. His current research is both laboratory based and clinical, with focus on elucidating the pathogenesis of inherited metabolic diseases caused by defects in the sterol and isoprenoid pathway and using induced pluripotent stem cells for the study of intellectual disability in patients with autism spectrum disorders. Dr. Roullet has served as Ad Hoc Reviewer for NIH/NIAAA, Atherosclerosis, Journal of Hypertension, and Journal of Inherited Metabolic Diseases, and he serves as a Member of the Medical Advisory Board for the SLO/RSH Foundation.

Biography Updated on 14 March 2011

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