Maureen E. Hoatlin

Oregon Health & Science University, USA

Maureen E. Hoatlin is an Associate Professor of biochemistry and molecular biology at Oregon Health & Science University (OHSU) in Portland, Ore, USA. After earning a B.S. degree in chemistry from Old Dominion University, she was a project chemist at SRI International in Menlo Park, Calif, for two years, followed by six years as a research associate at Genentech, Inc. She received a Ph.D. degree at Oregon Health & Science University in 1993 for graduate work focusing on the role of retroviruses in pathogenesis and hematopoietic cancers. She joined the faculty in Hematology & Medical Oncology at OHSU as a Research Assistant Professor in 1993, and was a Visiting Scientist and Professor at the Department of Genetics at the Free University and Medical Center of Amsterdam in 1998 and in 2002. Dr. Hoatlin’s current research is focused on identifying and analyzing the function of the proteins in the Fanconi Anemia/Breast Cancer (FA/BRCA) pathway. Her work has contributed to the discovery and characterization of seven novel human genes, many with critical but poorly understood roles in hematopoiesis, cancer susceptibility (AML and other cancers), and resistance to certain commonly used chemotherapeutic drugs. Dr. Hoatlin’s lab pioneered a cell-free approach to analyze the function of the FA/BRCA pathway and recently developed a novel small molecule inhibitor screen leading to the identification of FA/BRCA pathway inhibitors and potential chemosensitizing compounds. Dr. Hoatlin has served as a Reviewer for the NIH-NIMH Board of Scientific Counselors, NIH Hematology special study sections, and several International funding agencies. She is a frequent Reviewer for several journals including Blood, Cancer Research, Molecular and Cell Biology, Stem Cells, the Journal of Virology, and the Journal of Biological Chemistry. Dr. Hoatlin is a Member of the Knight Cancer Institute’s Leadership Council and the Hematologic Malignancies Program, and is a Coleader of the OHSU Cancer Biology Graduate program.

Biography Updated on 13 January 2010

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