Luca Cucullo

Texas Tech University Health Sciences Center, USA


Luca Cucullo is an Assistant Professor in the Department of Pharmaceutical Sciences at TTUHSC, St. Amarillo, TX, USA. Cucullo received his Doctoral degree in chemistry and pharmaceutical technology (biotechnology) from the School of Pharmacy, University of Pisa, Pisa, Italy, in 2000 and a postdoctoral training at the Cleveland Clinic, St. Cleveland, OH, USA (Department of Neurosurgery/Cerebrovascular Research Center) in in vitro cerebrovascular and blood-brain barrier (BBB) modeling. Cucullo’s research interests are largely focused on translational neuroscience encompassing both the study of neuroinflammatory mechanisms and cerebrovascular pathophysiology. These include cross-interactions between the cellular elements of the neurovascular unit as well as environmental and cellular modulation of BBB functions and their role in the pathogenesis of secondary brain injury and neuroinflammation (e.g., rheological and proinflammatory changes in ischemia and stroke). Cucullo’s research also focuses on unraveling the differential toxicity of standard and “reduced-exposure” tobacco products on the BBB and the biological links between cigarette smoke exposure and pathogenesis/progression of CNS disorders. This research encompasses both the study of neuroinflammatory mechanisms and cerebrovascular pathophysiology. Cucullo’s research programs are currently funded by the National Institute of Drug Abuse (R01-DA02912; effects of tobacco smoke toxicity at the blood-brain barrier) and Alternative Research and Development Foundation (effect of hyper- and hypoglycemia on BBB physiology). In addition to his research and teaching duties, Cucullo serves as Managing Editor and Lead Faculty in Neuroscience on WebmedCentral. He also serves as Associate Editor for the Oxidants and Antioxidants in Medical Science Journal and as Editorial Board Member for the Journal of Pharmacovigilance.

Biography Updated on 7 July 2013

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