Ernesto Picardi

Università degli Studi di Bari, Italy


Ernesto Picardi (EP) obtained his PhD in Plant Biology at the University of Calabria (Italy) in January 2006. In 2004 he got a “Marie Curie” fellowship at the EBI in Cambridge (UK) for training in software for molecular evolution and in scripting programming by Python language, under the supervision of Dr. N. Goldman. In February 2006 he was post-doc at the University of Bari in the group headed by Prof. G. Pesole. He also visited the Genome Bioinformatics Research Laboratory in Barcelona (Spain) directed by Prof. R. Guigo' acquiring specific skills in computational biology for gene finding and genome annotation. From May 2008 to present is Assistant Professor in Molecular Biology at the University of Bari and from 2010 is associated to IBBE-CNR Institute. EP started his research career working on RNA editing in plant mitochondria. Then he moved to alternative splicing and computational tools to predict gene structures in eukaryotic genomes. He published several papers concerning computational methodologies to handle expressed data and predict alternative splicing in animals and plants. He collaborated to the development of a web resource for studying alternative splicing in eukaryotes (ASPICdb) and to an updated version of UTRdb database focusing on untranslated regions of eukaryotes transcripts. The actual research interests concern the study of post-transcriptional events in animals and plants by using next generation sequencing technologies. EP developed the first methodology to predict de novo RNA editing events by massive transcriptome sequencing using reads from Illumina and SOLiD technologies. He is the main author of Expedit, a web service to investigate human RNA editing by RNA-Seq data. His interests also include the study of the relationship between RNA editing and alternative splicing and their roles in normal and pathological conditions.

Biography Updated on 1 April 2012

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