Fiorentina Ascenzioni

Sapienza University of Rome, Italy


Fiorentina Ascenzioni received a Diploma in biological science from the Sapienza University of Rome, Rome, Italy (1983) and a Ph.D. degree in natural science from the University of Tuebingen, Tuebingen, Germany (1987). She served as a Visiting Professor, École Normale Supérieure de Lyon, Lyon, France (1998 ‐1999), and a Group Leader at the Department of Cellular and Developmental Biology, Sapienza University of Rome, Rome, Italy (1991‐2001). Currently, she works as an Associate Professor of microbiology at the Department of Biology and Biotechnology C. Darwin, Sapienza University of Rome (since 2001). Ascenzioni is also a coordinator of LM cell biology and mentor of Ph.D. students. Her major scientific interests are host defense against P. aeruginosa in cystic fibrosis and bacterial mechanisms to subvert the host response; development of new therapeutics for cystic fibrosis: tagging the ENaC channel by RNA silencing, modulators of chromatin condensation, and antiprotease treatment to improve the function of CF epithelial cells; nanoparticle‐based anti‐inflammatory and antibacterial compounds; development of artificial chromosomes and episomal vectors for delivery of therapeutic genes; and telomere maintenance and DSBs repair mechanisms in yeast: the humanized yeast a puzzling structure.

Biography Updated on 11 November 2013

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