Charles Roselli

Oregon Health & Science University, USA


Charles Roselli was born in Harrisburg, Pa, USA, in 1952. He received a B.A. degree in biology from Franklin and Marshall College, Lancaster, Pa, USA, in 1974 and a Ph.D. degree from Hahnemann University (now Drexel University), Philidelphia, Pa, USA in 1981. From 1981 to 1984, Roselli was a Postdoctoral Fellow at the Laboratory of Dr. John A. Resko at the Oregon National Primate Center and Oregon Health and Science University (OHSU) in Portland. Dr. Roselli then became a faculty at the Department of Physiology and Pharmacology and has risen through the academic ranks to a Professor. His research is aimed at understanding the steroid-sensitive brain circuitry, neurochemical mechanisms, and the subcellular signaling pathways that mediate the central neuroendocrine and behavioral actions of androgens. A major research focus has been the characterization of the aromatase-signaling (estrogen synthetase) pathway in mammalian neural tissue. His recent studies are the domestic ram as an experimental model to understand the neurobiology and early programming of neural mechanisms underlying sexual attraction and the roles that gonadal steroids play in regulating this behavior. His research has led to the discovery of an ovine sexually dimorphic nucleus (oSDN) in the preoptic area that is enriched in aromatase-expressing neurons. In addition to his studies in the brain, Dr. Roselli also studies the effect of natural plant products and extracts on prostate cancer prevention and development. He is currently a Member of the Editorial Boards of Endocrinology and Hormones and Behavior.

Biography Updated on 21 November 2011

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