Barbara Pascucci was born in Rome, Italy, in 1969. She received a B.S. degree in biology (summa cum laude) from Sapienza University of Rome, Italy, in 1993. She obtained her professional qualification as a Biologist in 1995 and received the Post-Lauream specialization in biotechnology from the same university in 2002. From 1991 to 1993, she attended the Laboratory of Cellular Biology of University of Rome as a graduate student. She presented a thesis titled "Production and characterization of human Factor XII recombinant proteins devoid of specific structural domains". From 1993 to 1994, she worked as a Research Assistant at the same institution. From 1995 to 2001, she was a Research Fellow at the National Health Institute of Rome. During these years, she was a Visiting Scientist at the lab directed by R.P.P.Fuchs, Cancérogenese et Mutagenése Moleculaire, CNRS (Strasbourg), as a part of the project titled "An experimental strategy for detection of low frequency mutations in human DNA: towards an application in molecular epidemiology". She also worked in the lab directed by U. Hubscher, University of Zurich, Switzerland, specializing in the in vitro reconstitution of the long-patch base excision repair pathway. In 2001, she won a public competition and she got a permanent position as a Researcher at the Institute of Crystallography at the CNR in Rome. She won the SIMA (Italian Society Environmental Mutagenesis) Award for the best paper published on international journals in 1997. Dr. Pascucci has an extensive knowledge in the field of DNA damage response and DNA repair pathways in mammalian cells. In particular, she studied these cellular processes by biomolecular and biochemical experimental approaches. Currently, she is involved in projects drawn to investigate the crosstalk between DNA damage accumulation and degenerative diseases in postmitotic cells, such as neurons and myotubes.
Biography Updated on 8 December 2011