Nicole Thielens

Institut de Biologie Structurale, France


Nicole Thielens received her Biochemistry Engineer degree from the INSA (National Institute of Applied Sciences) of Lyon in 1978, and her M.S. and Ph.D. degrees from the University Joseph Fourier of Grenoble in 1979 and 1984, respectively. From 1978 to 1992, she was a Member of the Immunochemistry Laboratory of the CEA-Grenoble and spent one year as a Postdoc at the University of Florida, Gainesville in 1986-1987. Since 1992, she is a Research Scientist at the Institut de Biologie Structurale (IBS) of Grenoble, where she currently holds a position of Team Leader. She joined the INSERM (National Institute of Health and Medical Research) in 1986 and is appointed as Research Director since 2005. Her main scientific interests focus on the structure and function of (i) innate immune proteins involved in the recognition of pathogens and altered-self cells; (ii) their receptors and partner proteins involved in triggering immune effector mechanisms such as complement activation and enhancement of phagocytosis. She has expertise in specialized techniques including recombinant protein expression in insect and mammalian cells, protein engineering, and surface plasmon resonance (SPR) spectroscopy (she is responsible for the Biacore facility of the IBS).

Biography Updated on 9 August 2011

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