H. S. Chan

Hospital for Sick Children, Canada

H. S. Chan serves as a Professor of pediatrics at the University of Toronto since 1996, a Senior Scientist at the Research Institute of the Hospital for Sick Children since 1991. She also worked as a Hematologist/Oncologist at the division of hematology/oncology since 1979. She was a Fellow at the Royal College of Physicians and Surgeons of Canada since 1977 and a Fellow of the American Academy of Pediatrics since 1977. She is board certified in pediatrics (1977) and pediatric hematology/oncology (1978). Chan's research focus is multidrug resistance in childhood cancers, especially the rare eye cancer retinoblastoma (RB). Chan is an acknowledged expert who brought about a worldwide resurgence of using chemotherapy for treating RB, greatly improving the results of saving the vision and lives of children, avoiding radiation-induced secondary cancers. Chan is currently PI in a 2003-2009 Ontario Institute for Cancer Research-funded and 2010-2011 Terry Fox Research Institute-funded International Multicenter Trial using reversal of multidrug resistance to improve the response, without increasing the toxicity, of chemotherapy for RB, a successful treatment that he has piloted in Hospital for Sick Children clinical trials since 1991. She codirects a world-renown RB program with Dr. Gallie, and is consulted on RB problems worldwide. He held an NCIC Research Scientist Career Award (1990-1996), an NCIC Terry Fox Program Expansion Award (1991-1994), and a Terry Fox Program Project Award (1993-1996; Co-PI with Dr. Victor Ling). Chan has published extensively, including a book entitled Understanding Cancer Therapies (University Press of Mississippi, 2007). In 2010, Lieutenant Governor David Onley awarded Chan the Order Of Ontario, Ontario's Highest Honor, citing, Dr. Helen Chan of Toronto, an internationally renowned clinical oncologist, is recognized for her breakthrough treatment of retinoblastoma in children, a rare cancer of the eyes.

Biography Updated on 24 January 2011

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