Abstract
The aim. To evaluate the frequency
of gallstone formation and alteration of plasma lipid profiles in
SLE patients long treated with prednisolone. Material and methods.
Sixty patients with SLE were divided into 2 groups: (1) 38 SLE
patients without gallstones; (2) 22 SLE patients with gallstones.
Gallbladder ultrasonography was performed in all the patients, and
the serum lipid profile was determined. To identify the
composition and structure of gallstones obtained during
cholecystectomy, color cathodoluminescence scanning
electromicroscopy was used. Results. Gallstone disease was
detected in 22 (36.7%) patients of the 60 examinees and in 22
(68.8%) of the 32 SLE patients receiving prednisolone therapy;
whereas none of the 28 prednisolone-untreated patients was found
to have the disease (