Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model
Figure 3
Immunodensitometry of S100B at 10-and 28-weeks- in CD1 control and S100B transgenic mice. In (a), the S100B mice shown significantly () elevated S100B in CA3 stratum radiatum, the hilus, and molecular layers of the dentate gyrus. There is also a trend towards significance in CA1 stratum radiatum. In (b), all of these regions are significantly elevated (; ) at the 28 week time point.