Tumor Necrosis Factor Receptor 1 Expression Is Upregulated in Dendritic Cells in Patients with Chronic HCV Who Respond to Therapy
Table 2
TNFR1 Family Members’ mRNA Levels.
ControlHCV neg
Responders
NR/Rel
Prior to Tx
On Tx
Prior to Tx
On Tx
TNFR1
()()
1.94 for all 2.43 ()
7.09 for all 8.82 () ()
2.83 for all 2.87 ()
2.31 for all 3.53 () ()
TNFR2
()()
1.36 for all 1.22 ()
() ()
2.30 for all 2.67 ()
2.57 for all 4.60 () ()
LTR
()()
1.21 for all 1.24 ()
() ()
1.35 for all 1.35 ()
2.47 for all 5.41 () ()
FASR
0.38 for all 0.54 ()
0.001 ()
0.14 for all 0.40 () ()
0.01 for all 0.01 ()
0.03 for all 0.07 () ()
CD30
0.37 for all 0.41 ()
0.175 for all 0.06 ()
0.61 for all 1.22 () ()
0.06 for all 0.07 ()
0.61 for all 1.51 () ()
CD27
0.86 for all 0.49 ()
0.77 for all 0.37 ()
1.08 for all 0.65 () ()
1.10 for all 0.62 ()
0.71 for all 0.62 () ()
NGF
0.75 for all 1.22 ()
0.085 for all 0.007 ()
1.85 for all 4.80 () ()
0.11 for all 0.19 ()
1.37 for all 2.86 () ()
IL-2R for all
0.22 for all 0.39 ()
0.175 for all 0.18 ()
0.45 for all 0.63 () ()
0.10 for all 0.22 (
0.05 for all 0.10 () ()
CD3
1.43 for all 0.71 ()
1.3 ()
4.71 for all 12.62 () ()
1.67 for all 1.07 ()
6.93 for all 21.06 () ()
Include End of treatment responders (ETR) and SVR. Mean value for control liver disease patients, HCV negative. -value compared to control (HCV negative, age and sexed matched).
