Cardiovascular Psychiatry and Neurology

Review Article

S100B Serum Levels in Schizophrenia Are Presumably Related to Visceral Obesity and Insulin Resistance

Table 1

Demographics and clinical measurements of control subjects and patients with paranoid schizophrenia. Annotation: data are given as mean standard deviation (SD), n.a. = not applicable, NOVA, hi-square-test, NCOVA, positive or negative influence on measures, bold P-values were significant, underlined P-values remained significant after Bonferroni correction.


Demographic data	Controls ()	Paranoid schizophrenia ()	P-values
Demographic data	Controls ()	Paranoid schizophrenia ()	Schizophrenia versus controls

Age []	34.4 10.8	34.7 11.3	0.91
Duration of disease []	—	8 9	n.a.
Male/Female []			0.82
BMI [kg/]	24.3 3.8	27.7 5.7	0.19
Smokers/non-smokers []			0.17

Clinical data/measures	Mean SD	Mean SD	Influence of diagnosis (uncorrected ANOVA)	Influence of diagnosis (ANCOVA)	Influence of BMI (ANCOVA)
PANSS total score	—		n.a.	n.a.	—
PANSS positive score	—		n.a.	n.a.	—
PANSS negative score	—		n.a.	n.a.	—
PANSS general score	—		n.a.	n.a.	—

S100B [g/L]			0.01	0.03	0.38

hs-CRP [mg/L]			0.07	0.51
TNF- [ng/L]			0.05	0.19	0.10
Leptin [g/L]			0.09	0.62
MCP-1 [ng/L]			0.03	0.40
HGF [g/L]			0.05	0.48
Resistin [g/L]			0.68	0.89	0.46
PAI-1 [g/L]			0.00	0.04	0.04

Triglycerides [mg/dL]			0.02	0.08	0.12
Glucose [mg/dL]					0.89
C-peptide [pmol/L]					0.21