64-year-old female suffering from a left-sided tongue cancer. (a) shows the MIP (maximum intensity projection)—image of SPECT acquisition in anteroposterior view. A large uptake is seen at the injection site with a small, focal uptake of the left lower boarder (cross hair). (b) shows a fused coronal SPECT/CT image that localises the small focal uptake in the neck region level IIA/B. (c) shows the axial SPECT image with the corresponding cross hair in the sentinel node with a clear delineation from the injection site. (d) shows the corresponding low-dose CT scan localising the uptake by linked cross hair into the neck level IIA/B.