Review Article

A Review on the Chemistry of Eremanthine: A Sesquiterpene Lactone with Relevant Biological Activity

Scheme 41

Synthesis of the compound 166 in mixture with the lactone 159: (a) (i) KOH-H2O; (ii) Dryness; (iii) MsCl, Et3N, THF (conc.); (iv) NaOH-H2O; (v) HCl-H2O.
170196.sch.0041