Research Article

Dissemination and Molecular Epidemiology of KPC-Producing Klebsiella pneumoniae Collected in Puerto Rico Medical Center Hospitals during a 1-Year Period

Table 3

MIC-50, MIC-90, and % susceptible of 27 KPC-producing K. pneumoniae Isolates.

Test agentRange (μg/mL)MIC50 (μg/mL)MIC90 (μg/mL)% susceptible (no. of susceptible/no. of tested isolates)

Piperacillin/tazobactam32/4–>128/4>128/4>128/40
Cefoxitin≤4–>6416>6437 (10/27)
Ceftazidime16–>128321280
Ceftriaxone4–>12832>12811 (3/27)
Cefepime≤4–>32≤43259 (16/27)
Aztreonam16–>32>32>320
Ertapenem≤2–>16≤2>160
Imipenem≤0.5–>1621633 (9/27)
Meropenem≤1–>84>837 (10/27)
Trimethoprim/sulfamethoxazole≤0.5–>4>4>426 (7/27)
Ciprofloxacin≤0.5–>4>4>433 (9/27)
Gentamicin≤2–>168>1630 (8/27)
Amikacin≤8–32≤81689 (24/27)
Tigecycline≤1–4≤1≤1100 (27/27)