Research Article

Inhalation of Ortho-Phthalaldehyde Vapor Causes Respiratory Sensitization in Mice

Table 1

Inhalation of OPA skews the lymphocyte population heavily towards B lymphocytes in the mandibular lymph nodes.

OPA (ppb)T-lymphocyte/B-lymphocyte Ratio
(Fold change from concurrent control)

Sensitization Exposure
125 a
250
500 *
1000 *

Sensitization/Challenge Exposure
125 *
250 *
500 *
1000 *

*Significantly different from concurrent control group at .
aMean ± SEM ( ).