Research Article

Investigating Potential Associations between Cervical Procedures and HIV Acquisition

Table 2

Effect of cervical procedures at any time on risk of HIV acquisition.

VariableHIV acquisition 𝑛 / 𝑁 (%)Unadjusted relative risk (95% CI) 𝑃 valueAdjusted* relative risk (95% CI) 𝑃 value

Cervical biopsy
No biopsy
6/142 (4.2)
78/1885 (4.1)
1.02 (0.43–2.38)0.960.92 (0.39–2.16)0.85

ECC
No ECC
2/137 (1.4)
82/1890 (4.3)
0.32 (0.07–1.34)0.120.29 (0.07–1.22)0.09

LEEP
No LEEP
3/64 (4.7)
81/1963 (4.1)
1.14 (0.35–3.71)0.831.00 (0.30–3.30)0.99

Any procedure
No procedure
7/199 (3.5)
77/1828 (4.2)
0.82 (0.37–1.82)0.640.74 (0.33–1.65)0.47

CI indicates confidence interval, ECC: endocervical curettage, LEEP: loop electrosurgical excision procedure.
*Adjusted for the following baseline variables: positive serology for HSV-2, high-risk partner as defined in Table 1’s footnote, sometimes or always using condoms (compared to no condom use) within the last 3 months.