Research Article

Mixed-Ligand Nickel(II) Complexes Containing Sulfathiazole and Cephalosporin Antibiotics: Synthesis, Characterization, and Antibacterial Activity

Table 3

Antibacterial activity of the drugs and the complexes.

CompoundZone of inhibition (mm)
E.C.S.E.P.A.S.AK.P.B.S.

Cefazolin
Ni(L1)(stz)(H2O)
Cephalothin
Ni(L2)(stz)
Cefotaxime
Ni(L3)(stz)
Ceftriaxone
Ni(L4)(stz)(H2O)
Cefepime
Ni(L5)(stz) Cl
Sulfathiazole

E.C., Escherichia coli ATCC 35939; S.E., Salmonella enteritidis ATCC 497; P.A., Pseudomonas aeruginosa ATCC 10145; S.A., Staphylococcus aureus ATCC 25923; K.P., Klebsiella pneumonia ATCC 10031; B.S., Bacillus subtilis ATCC 6051. Values are the mean ± Standard deviation of the mean.