| | Manifestations | Treatments |
| | Oral ulcers | 1st line: Topical triamcinolone acetonide, prednisolone, amlexonax, anti-inflammatory rinses, topical anaesthetics | | 2nd line: Topical sucralfate, aminosalicylic acid, caustic solutions, oral tetracycline solutions, colchicine, levamisole, thalidomide, pulse methyl prednisolone, intralesional trimcinolone acetonide | | 3rd line: Cyclosporine, azathiopurine, methotrexate, chlorambucil, infliximab, etanercept, plasmapheresis-apheresis, zinc sulphate, penicilline, azithromycin, minocycline, dapsone, pentoxifylline, interferon-α |
| | Genital ulcers | 1st line: Topical triamcinolone acetonide, sucralfate, oral colchicine, azathiopurine, dapsone, prednisolone | | 2nd line: Levamisole, interferon-α, methotrexate, thalidomide, cyclosporine A |
| | Vasculitic ulcerations | 1st line: Topical bethametasone, oral colchicine, azathiopurine, dapsone, prednisolone | | 2nd line: Levamisole, dapson, interferon-α, thalidomide, azitromycin, pentoxifylline |
| | Gastrointestinal involvement | 1st line: Sulfasalazine, corticosteroids | | 2nd line: Cyclosporine A, azathiopurine, surgery | | 3rd line: İntraarterial corticosteroids injections |
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